Леонов Сергей Викторович

Онкология, гены-супрессоры опухоли, р53, р63, р73, радиотерапия, полиплоидные гигантские опухолевые клетки, нейродегенерация, повреждения и репарация ДНК, клеточная гибель, деменция, Болезнь Альцгеймера и Паркинсона, сигналинг через G-белок связанные рецепторы, фармакология взаимодействия лиганд-рецептор, разработка лекарственных препаратов

1) Pustovalova, M.; Blokhina, T.; Alhaddad, L.; Chigasova, A.; Chuprov-Netochin, R.; Veviorskiy, A.; Filkov, G.; Osipov, A.N.; Leonov, S. CD44+ and CD133+ Non-Small Cell Lung Cancer Cells Exhibit DNA Damage Response Pathways and Dormant Polyploid Giant Cancer Cell Enrichment Relating to Their p53 Status. Int. J. Mol. Sci. 2022, 23, 4922. https://doi.org/10.3390/ijms23094922 ; (IF= 6.208), Q1
2) Fokin, Artem I.; Chuprov-Netochin, Roman N.; Malyshev, Alexander S.; Romero, Stéphane; Semenova, Marina N.; Konyushkin, Leonid D.; Sergey V Leonov, Victor V Semenov (2022): Synthesis, Screening and Characterization of Novel Potent Arp2/3 Inhibitory Compounds Analogous to CK-666. Frontiers in Pharmacology. Collection. https://doi.org/10.3389/fphar.2022.896994; (IF= 5.988), Q1
3) Mohamed H, Marusich E, Afanasev Y, Leonov S. Bacterial Outer Membrane Permeability Increase Underlies the Bactericidal Effect of Fatty Acids From Hermetia illucens (Black Soldier Fly) Larvae Fat Against Hypermucoviscous Isolates of Klebsiella pneumoniae. Front Microbiol. 2022 May 6;13:844811. doi: 10.3389/fmicb.2022.844811; (IF= 5.64), Q1.
4) Lu L, Zhang Y, Tan X, Merkher Y, Leonov S, Zhu L, Deng Y, Zhang H, Zhu D, Tan Y, Fu Y, Liu T, Chen Y. Emerging mechanisms of pyroptosis and its therapeutic strategy in cancer. Cell Death Discov. 2022 Jul 27;8(1):338. doi: 10.1038/s41420-022-01101-6. PMID: 35896522; PMCID: PMC9329358; (IF= 7.109), Q2.
5) Chernyshev, V. S., Chuprov-Netochin, R. N., Tsydenzhapova, E., Svirshchevskaya, E. V., Poltavtseva, R. A., Merdalimova, A., Yashchenok, A., Keshelava, A., Sorokin, K., Keshelava, V., Sukhikh, G. T., Gorin, D., Leonov S, M., & Skliar, S. (2022). Asymmetric depth-filtration: A versatile and scalable method for high-yield isolation of extracellular vesicles with low contamination. Journal of Extracellular Vesicles, 11, e12256. https://doi.org/10.1002/jev2.12256; (IF= 21.224), Q1.
6) Li, Y., Zhang, H., Merkher, Y. et al. Recent advances in therapeutic strategies for triple-negative breast cancer. J Hematol Oncol 15, 121 (2022). https://doi.org/10.1186/s13045-022-01341-0, (IF= 14.571), Q1
7) Alhaddad, L.; Osipov, A.N.; Leonov, S. The Molecular and Cellular Strategies of Glioblastoma and Non-Small-Cell Lung Cancer Cells Conferring Radioresistance. Int. J. Mol. Sci. 2022, 23, 13577. https://doi.org/10.3390/ijms232113577 ; (IF= 6.208), Q1
8) Dayoub, A.; Fokin, A.I.; Lomakina, M.E.; James, J.; Plays, M.; Jacquin, T.; Novikov, N.M.; Vorobyov, R.S.; Schegoleva, A.A.; Rysenkova, K.D.; Gaboriaud, J.; Leonov, S.V.; Denisov, E.V.; Gautreau, A.M.; Alexandrova, A.Y. Inactivation of PTEN and ZFHX3 in Mammary Epithelial Cells Alters Patterns of Collective Cell Migration. Int. J. Mol. Sci. 2023, 24, 313. https://doi.org/10.3390/ijms24010313; (IF= 6.208), Q1