Professional interests/research projects:
Development of methods of systems biology, analysis of interactomes, quantitative characterization of the intensity of intermolecular interactions. Using OMICS data to find new solutions for the treatment of chronic diseases. Diagnostic systems of new generation.
Main publications:
- Buzdin A, Sorokin M, Garazha A, Glusker A, Aleshin A, Poddubskaya E, Sekacheva M, Kim E, Gaifullin N, Giese A, Seryakov A, Rumiantsev P, Moshkovskii S, Moiseev A. RNA sequencing for research and diagnostics in clinical oncology. Semin Cancer Biol. 2020 Feb;60:311-323. doi: 10.1016/j.semcancer.2019.07.010. Epub 2019 Aug 11. PMID: 31412295.
- Buzdin A, Sorokin M, Garazha A, Sekacheva M, Kim E, Zhukov N, Wang Y, Li X, Kar S, Hartmann C, Samii A, Giese A, Borisov N. Molecular pathway activation - New type of biomarkers for tumor morphology and personalized selection of target drugs. Semin Cancer Biol. 2018 Dec;53:110-124. doi: 10.1016/j.semcancer.2018.06.003. Epub 2018 Jun 20. PMID: 29935311.
- Buzdin A, Tkachev V, Zolotovskaia M, Garazha A, Moshkovskii S, Borisov N, Gaifullin N, Sorokin M, Suntsova M. Using proteomic and transcriptomic data to assess activation of intracellular molecular pathways. Adv Protein Chem Struct Biol. 2021;127:1-53. doi: 10.1016/bs.apcsb.2021.02.005. Epub 2021 Apr 5. PMID: 34340765.
- Sorokin M, Borisov N, Kuzmin D, Gudkov A, Zolotovskaia M, Garazha A, Buzdin A. Algorithmic Annotation of Functional Roles for Components of 3,044 Human Molecular Pathways. Front Genet. 2021 Feb 9;12:617059. doi: 10.3389/fgene.2021.617059. PMID: 33633781; PMCID: PMC7900570.
- Zolotovskaia M, Tkachev V, Sorokin M, Garazha A, Kim E, Kantelhardt SR, Bikar SE, Zottel A, Šamec N, Kuzmin D, Sprang B, Moisseev A, Giese A, Efimov V, Jovčevska I, Buzdin A. Algorithmically Deduced FREM2 Molecular Pathway Is a Potent Grade and Survival Biomarker of Human Gliomas. Cancers (Basel). 2021 Aug 16;13(16):4117. doi: 10.3390/cancers13164117. PMID: 34439271; PMCID: PMC8394245.
- Kim EL, Sorokin M, Kantelhardt SR, Kalasauskas D, Sprang B, Fauss J, Ringel F, Garazha A, Albert E, Gaifullin N, Hartmann C, Naumann N, Bikar SE, Giese A, Buzdin A. Intratumoral Heterogeneity and Longitudinal Changes in Gene Expression Predict Differential Drug Sensitivity in Newly Diagnosed and Recurrent Glioblastoma. Cancers (Basel). 2020 Feb 24;12(2):520. doi: 10.3390/cancers12020520. PMID: 32102350; PMCID: PMC7072286.
- Zolotovskaia MA, Tkachev VS, Seryakov AP, Kuzmin DV, Kamashev DE, Sorokin MI, Roumiantsev SA, Buzdin AA. Mutation Enrichment and Transcriptomic Activation Signatures of 419 Molecular Pathways in Cancer. Cancers (Basel). 2020 Jan 22;12(2):271. doi: 10.3390/cancers12020271. PMID: 31979117; PMCID: PMC7073226.
SPIN РИНЦ:
3774-4280
Researcher ID:
R-2611-2016
Scopus Author ID:
36811984500
ORCID:
0000-0001-9866-3424
H-index
37
General
School
Educational programs
School structure
© 2001-2022 Moscow Institute of Physics and Technology (National Research University)
Social networks
Language version
Site Search