PhD in Biology

Scientific supervisor

Sheida Frolova

Main place of work:

M. F. Vladimirsky Moscow Regional Research Clinical Institute

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Professional interests/research projects:

Study of various pathologies of the heart, the effect of drugs on ionic cardiomyocytes at the cellular level
Main publications:
1. Frolova SR, Gorbunov VS, Shubina NS, Perepukhov AM, Romanova SG, Agladze KI. Stilbene derivative as a photosensitive compound to control the excitability of neonatal rat cardiomyocytes. Biosci Rep. 2019 Jan 25;39(1):BSR20181849. doi: 10.1042/BSR20181849. PMID: 30630877; PMCID: PMC6419148.
2. Podgurskaya AD, Slotvitsky MM, Tsvelaya VA, Frolova SR, Romanova SG, Balashov VA, Agladze KI. Cyclophosphamide arrhythmogenicitytesting using human-induced pluripotent stem cell-derived cardiomyocytes. Sci Rep. 2021 Jan 27;11(1):2336. doi: 10.1038/s41598-020-79085-5. PMID: 33504826; PMCID: PMC7841168.
3. Frolova SR, Gaiko O, Tsvelaya VA, Pimenov OY, Agladze KI. Photocontrol of Voltage-Gated Ion Channel Activity by Azobenzene Trimethylammonium Bromide in Neonatal Rat Cardiomyocytes. PLoS One. 2016 Mar 25;11(3):e0152018. doi: 10.1371/journal.pone.0152018. PMID: 27015602; PMCID: PMC4807758.
4. Podgurskaya AD, Tsvelaya VA, Frolova SR, Kalita IY, Kudryashova NN, Agladze KI. Effect of heptanol and ethanol on excitation wave propagation in a neonatal rat ventricular myocyte monolayer. Toxicol In Vitro. 2018 Sep;51:136-144. doi: 10.1016/j.tiv.2018.05.009. Epub 2018 May 17. PMID: 29778719.
5. Slotvitsky M. et al. Arrhythmogenicity test based on a human-induced pluripotent stem cell (iPSC)-derived cardiomyocyte layer //Toxicological Sciences. – 2019. – Т. 168. – №. 1. – С. 70-77.
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