PhD in Biology

Scientific supervisor

Elena Marusich

Main place of work:

MIPT, Laboratory for the Development of Innovative Medicines and Agrobiotechnologies

Write to the mail

Contacts:

marusich.ei@mipt.ru

Professional interests/research projects:

The study of alternative means of combating pathogenic microorganisms to antibiotics based on extracts from the fat of the Black Lion fly larvae. small molecules isolated from natural plants of the Altai Territory, as well as from spirulina). Study of the effect of metabolic stress and autophagy on the decrease in the neurotoxicity of human Aβ1-42 amyloid in the Caenorhabditis elegans model of Alzheimer's disease. Search for new modulators of growth and development of agricultural plants (development of essays and proof of biological activity on model and agricultural plants). Development of a medical product based on spirulina, which is active against psoriasis.

Main publications:
1) Mohamed H, Marusich E, Afanasev Y, Leonov S. Fatty Acids-Enriched Fractions of Hermetia illucens (Black Soldier Fly) Larvae Fat Can Combat MDR Pathogenic Fish Bacteria Aeromonas spp. Int J Mol Sci. 2021 Aug 17;22(16):8829. doi: 10.3390/ijms22168829.
 PMID: 34445533 (Q1)
2) Elena Marusich, Heakal Mohamed? Yuriy Afanasen and Sergey Leonov. Fatty acids Hermitia illucebs larvae fat unhibit the proliferation and growth of actual phytopathogens. Microorganisms 2020, 8, 1423; doi:10.3390/microorganisms8091423 (Q1)
3) ) Guvatova Z, Dalina A, Marusich E, Pudova E, Snezhkina A, Krasnov G, Kudryavtseva A, Leonov S, Moskalev A.Protective effects of carotenoid fucoxanthin in fibroblasts cellular senescence. Mech Ageing Dev. 2020 Jul;189:111260. doi: 10.1016/j.mad.2020.111260. Epub 2020 May 24.PMID: 32461144 (Q1)
4) Chuprov-Netochin R; Tsyganov D; Semenov V; Semenova M; Volynchuk P; Marusich E; Nazarenko V; Leonov S. «In vitro/in vivo antimitotic activity and structure-activity relationships of New Glaziovianin A Isoflavone Series» // Febs Journal 2016, 283, 158 (Q1)
5) Lashmanova E, Proshkina E, Zhikrivetskaya S, Shevchenko O, Marusich E, Leonov S, Melerzanov A, Zhavoronkov A, Moskalev A.Fucoxanthin increases lifespan of Drosophila melanogaster and Caenorhabditis elegans.Pharmacol Res. 2015 Oct;100:228-41. doi: 10.1016/j.phrs.2015.08.009. Epub 2015 Aug 18. PMID: 26292053 (Q1)
6) Chuprov-Netochin R, Marusich E, Neskorodov Y, Mishutkina Y, Volynchuk P, Ivanenkov Y, Touraev A, Leonov S, Palme K. Method for Ultrarapid High-Content Screening for Biologically Active Chemicals Using Plant Pollen. Methods Mol Biol. 2018;1795:27-37. doi: 10.1007/978-1-4939-7874-8_3. PMID: 29846916 (Q1)
7) V. V. Semenov, D. V. Tsyganov, M. N. Semenova, R.N. Chuprov-Netochin, M. M. Raihstat, L. D. Konyushkin, P. B. Volynchuk, E.I. Marusich, V.V. Nazarenko, S.V. Leonov, and A. S. Kiselyov. Efficient Synthesis of Glaziovianin A Isoflavone Series from Dill and Parsley Extracts and Their in Vitro/in Vivo Antimitotic Activity // J Nat Prod. 2016;79(5):1429-38. doi:10.1021/acs.jnatprod.6b00173. IF 3.798 (Q1)

SPIN РИНЦ:
нет
Researcher ID:
5130080
Scopus Author ID:
6602233707
ORCID:
0000-0003-1943-6245
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