Mikhail Vysokikh

Research in the field of mitochondrial bioenergetics and cell physiology, the study of the molecular mechanisms of aging

1. Braude S, Holtze S, Begall S, Brenmoehl J, Burda H, Dammann P, Del Marmol D, Gorshkova E, Henning Y, Hoeflich A, Höhn A, Jung T, Hamo D, Sahm A, Shebzukhov Y, Šumbera R, Miwa S, Vyssokikh MY, von Zglinicki T, Averina O, Hildebrandt TB. Surprisingly long survival of premature conclusions about naked mole-rat biology. Biol Rev Camb Philos Soc. 2021 Apr;96(2):376-393. doi: 10.1111/brv.12660. Epub 2020 Oct 30. PMID: 33128331.
2. Vyssokikh MY, Holtze S, Averina OA, Lyamzaev KG, Panteleeva AA, Marey MV, Zinovkin RA, Severin FF, Skulachev MV, Fasel N, Hildebrandt TB, Skulachev VP. Mild depolarization of the inner mitochondrial membrane is a crucial component of an anti-aging program. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6491-6501. doi: 10.1073/pnas.1916414117. Epub 2020 Mar 9. PMID: 32152094; PMCID: PMC7104298.
3. Shilovsky GA, Putyatina TS, Ashapkin VV, Yamskova OV, Lyubetsky VA, Sorokina EV, Shram SI, Markov AV, Vyssokikh MY. Biological Diversity and Remodeling of Cardiolipin in Oxidative Stress and Age-Related Pathologies. Biochemistry (Mosc). 2019 Dec;84(12):1469-1483. doi: 10.1134/S000629791912006X. PMID: 31870251.
4. Mikhailov KV, Efeykin BD, Panchin AY, Knorre DA, Logacheva MD, Penin AA, Muntyan MS, Nikitin MA, Popova OV, Zanegina ON, Vyssokikh MY, Spiridonov SE, Aleoshin VV, Panchin YV. Coding palindromes in mitochondrial genes of Nematomorpha. Nucleic Acids Res. 2019 Jul 26;47(13):6858-6870. doi: 10.1093/nar/gkz517. PMID: 31194871; PMCID: PMC6649704.
5. Shabalina IG, Vyssokikh MY, Gibanova N, Csikasz RI, Edgar D, Hallden-Waldemarson A, Rozhdestvenskaya Z, Bakeeva LE, Vays VB, Pustovidko AV, Skulachev MV, Cannon B, Skulachev VP, Nedergaard J. Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1. Aging (Albany NY). 2017 Feb 15;9(2):315-339. doi: 10.18632/aging.101174. PMID: 28209927; PMCID: PMC5361666.
6. Skulachev VP, Holtze S, Vyssokikh MY, Bakeeva LE, Skulachev MV, Markov AV, Hildebrandt TB, Sadovnichii VA. Neoteny, Prolongation of Youth: From Naked Mole Rats to "Naked Apes" (Humans). Physiol Rev. 2017 Apr;97(2):699-720. doi: 10.1152/physrev.00040.2015. PMID: 28202600.
7. Chugunova A, Loseva E, Mazin P, Mitina A, Navalayeu T, Bilan D, Vishnyakova P, Marey M, Golovina A, Serebryakova M, Pletnev P, Rubtsova M, Mair W, Vanyushkina A, Khaitovich P, Belousov V, Vysokikh M, Sergiev P, Dontsova O. LINC00116 codes for a mitochondrial peptide linking respiration and lipid metabolism. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4940-4945. doi: 10.1073/pnas.1809105116. Epub 2019 Feb 22. PMID: 30796188; PMCID: PMC6421467.